95%
↓ TB deaths by 2035
90%
↓ Incidence rate
0%
Catastrophic costs

🏛️ Pillar 1: Integrated, patient-centred care and prevention

Early diagnosis

Universal drug-susceptibility testing & systematic screening of contacts/high-risk groups.

Treatment for all

Including drug-resistant TB and patient support.

TB/HIV & co-morbidities

Collaborative activities, management of co-morbidities.

Preventive treatment

Vaccination & preventive therapy for high-risk persons.

⚙️ Pillar 2: Bold policies and supportive systems

Political commitment

Adequate resources for TB care and prevention.

Community engagement

Civil society, public & private care providers.

Universal health coverage

Regulatory frameworks, vital registration, rational medicines.

Social protection

Poverty alleviation & actions on TB determinants.

🔬 Pillar 3: Intensified research and innovation

Discovery & uptake

New tools, interventions, strategies.

Implementation research

Optimize impact and promote innovations.

New vaccine by 2025

Pre- and post-exposure effective vaccine needed.

Ending the TB epidemic: feasibility & action

Ending the global TB epidemic is feasible with dramatic decline in TB deaths and cases, and elimination of economic and social burden of TB. Failure to do so will carry serious individual and global public health consequences.

Achievement by 2035 requires: expanding scope of interventions, engaging wider collaborators across governments and private sector, and pursuing new scientific knowledge that can dramatically change TB prevention and care.

Projected acceleration: The annual decline in global TB incidence rates must accelerate from 2% per year (2015) to 10% per year by 2025. The case‑fatality ratio needs to decline from 15% (2015) to 6.5% by 2025. With optimized current tools and universal health coverage, plus new tools (vaccines, treatment for latent infection) by 2025, the 2035 targets become attainable.

📈 Reaching the targets: 2025 milestones

Annual decline in global TB incidence: from 2% (2015) to 10% by 2025. Case‑fatality ratio reduction from projected 15% to 6.5%. This is ambitious but feasible with existing tools complemented by universal health coverage and social protection. Beyond 2025, new tools such as an effective vaccine and safer latent infection treatment are required to reduce the 2 billion infected population reservoir.

SDG 2030 & End TB 2035 milestones — immediate investments in research & development are essential for new diagnostics, shorter drug regimens and vaccine.

Editor & citation

World Health Organization. (2015). The end TB strategy. World Health Organization. WHO/HTM/TB/2015.19. 20 pages.